For Research Purposes Only · Not For Human Consumption
C-terminal α-MSH tripeptide (Lys-Pro-Val). Researched for NF-κB suppression, gut inflammation and mast-cell modulation.
£24.99
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UK Peptides Quality Standards
Every batch is independently HPLC-tested by a third-party laboratory. Lot-matched Certificates of Analysis are available on request. For any quality-related query, contact support with your batch number and order ID.
What ships with your order
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of α-melanocyte stimulating hormone (α-MSH), retaining significant anti-inflammatory activity of the parent peptide while lacking pigmentary effects. Published research has documented NF-κB pathway suppression, mast-cell stabilisation and protective effects in models of inflammatory bowel disease and skin inflammation. ≥98% HPLC, third-party CoA.
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of α-melanocyte stimulating hormone (α-MSH), retaining significant anti-inflammatory activity of the parent peptide while lacking pigmentary effects. Extensively researched for NF-κB suppression, mast-cell stabilisation and protective effects in inflammatory bowel disease and skin inflammation models. UK Peptides supplies KPV 10mg as ≥98% HPLC lyophilised powder with a signed third-party Certificate of Analysis.
KPV consists of just three amino acids — lysine, proline and valine — corresponding to residues 11-13 of α-MSH. Despite its small size, KPV retains a substantial fraction of α-MSH's anti-inflammatory activity in multiple research models while being pharmacokinetically simpler, more stable, and free of melanocortin receptor pigmentary effects. It is one of the smallest bioactive peptides in the current research literature.
Published research has documented KPV suppression of NF-κB activation in immune cells, inhibition of pro-inflammatory cytokine release (TNF-α, IL-6, IL-8), mast-cell stabilisation reducing histamine release, and protective effects on epithelial barrier integrity in gut and skin models. Its mechanism appears to be substantially receptor-independent — cytoplasmic uptake and direct interference with inflammatory transcription factor activation is one leading hypothesis in the literature.
Published research has investigated KPV in inflammatory bowel disease (Crohn's and ulcerative colitis) models, atopic dermatitis and psoriasis research, mast-cell and allergy pathway studies, epithelial barrier integrity research, wound-healing inflammatory-phase studies, and comparative anti-inflammatory pharmacology against BPC-157 and other repair peptides. The 10mg vial supports extended research protocols.
Store the lyophilised vial at -20°C, sealed and protected from light. Reconstitute with bacteriostatic water (0.9% benzyl alcohol) — typically 1–2ml per 10mg vial. Add solvent slowly down the side of the vial; do not shake. Refrigerate the reconstituted solution at 2–8°C and use within 28 days. Do not refreeze after reconstitution.
Every KPV 10mg lot is independently HPLC-UV tested to ≥98% purity by Janoshik Analytical or Aspen Bioanalytics, with mass-spectrometry identity confirmation against the published molecular weight of 342.44 Da. The signed PDF Certificate of Analysis is supplied with every order and matches the vial lot number.
UK-stocked, same-day Manchester dispatch, third-party HPLC verification on every batch and Royal Mail Tracked 24 with insulated cold-chain packaging. Full lot traceability from vial sticker to signed CoA visible on this page.
Common search terms for this compound
KPV is the C-terminal tripeptide (Lys-Pro-Val) of α-melanocyte-stimulating hormone (α-MSH). It retains a substantial fraction of α-MSH's documented anti-inflammatory activity in cell and animal models while lacking the pigmentary activity mediated by the full peptide's binding to MC1R.
Regulatory & compliance notice
This product is supplied strictly for in-vitro laboratory research. It is not a licensed medicine in the United Kingdom, is not approved by the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency for human or veterinary use, and is not intended to diagnose, treat, cure or prevent any disease. Nothing on this page constitutes medical advice.
External links point to primary literature or regulatory records and open in a new tab. Citations are provided so the reader can independently verify every factual claim made on this page. Last reviewed 22 July 2026.
Certificate of Analysis
KPV 10mg
The CoA you download is the exact certificate produced for this lot — no edits.
Storage & handling
Keep it stable, keep it sterile
4.9
out of 5
Every review below comes from a confirmed UK Peptides customer who received and used this exact product. We do not edit, filter or remove low ratings.
"Spot-checked the KPV 10mg vial against an in-house standard and the identity match was clean. Purity on our column was 99.1%, consistent with the supplied CoA. Exactly the standard a lab needs."
Dr. R. Okafor · 2025-06-26
"Same-day dispatch is the real differentiator. Ordered KPV 10mg late afternoon and still made the Royal Mail cut-off. Tracking was live within two hours. Genuinely impressive turnaround."
C. Bowen · 2025-06-19
"Sourced KPV 10mg previously from a European supplier — UK Peptides is the same quality with half the delivery time and a proper UK invoice. Switching was an easy decision."
E. Lindqvist · 2025-06-12
"Solid all round. KPV 10mg purity verified independently and matched the CoA closely. Only minor feedback is that the order confirmation email could include the CoA attached automatically rather than as a portal link."
P. Donovan · 2025-06-05
"Have stopped sourcing KPV 10mg from anywhere else. The combination of verified purity, same-day dispatch, proper cold chain and a real UK address gives a level of trust the grey market simply cannot match."
M. Yusuf · 2025-05-29
"Ordered KPV 10mg on behalf of a university research group. Invoicing was clean, the CoA was acceptable to our procurement team without amendment, and the vial passed our internal QC on first inspection."
Dr. K. Sandhu · 2025-05-22
Showing a sample of 20 most recent written reviews from 2,116 total verified customer reviews.
Peer-referenced articles from our research library covering mechanism, evidence and handling.
Research Article
BPC-157 is a synthetic pentadecapeptide derived from a protein isolated in human gastric juice. Structure, mechanism and research history summarised.
Read article →
Research Article
BPC-157 structure: 15-amino-acid pentadecapeptide with sequence GEPPPGKPADDAGLV. Rich in proline residues, contributing to unusual stability.
Read article →
Research Article
BPC-157 stands for 'Body Protection Compound 157' — a name coined by the Zagreb research group describing its studied protective effects.
Read article →
Research Article
BPC-157 mechanism research: multiple pathways proposed including nitric oxide system modulation, growth-factor interactions, and angiogenesis.
Read article →
Research Article
BPC-157's parent protein was identified in human gastric juice. The 15-residue synthetic fragment is derived from this larger native protein.
Read article →
Research Article
BPC-157 studied effects across the peer-reviewed literature: gastric protection, tendon/ligament repair, angiogenesis, and neurological injury models.
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Recovery / Healing
BPC-157 · 5mgBody Protection Compound-157. Widely researched for tissue repair, gut health and joint recovery.
£15.99
Skin / Anti-Ageing Blend
KLOW · 80mgHigh-payload copper peptide + repair blend. KPV + GHK-Cu + BPC-157 + TB-500 co-lyophilised for advanced collagen and connective-tissue research.
£69.99
Accessories / Reconstitution
Bacteriostatic Water · 3ml0.9% benzyl alcohol bacteriostatic water for peptide reconstitution. Pharmaceutical-grade, sterile-filtered 3ml vial.
£4.99
Every batch independently tested by Janoshik Analytical and Aspen Bioanalytics before dispatch. Signed certificates available on every product page.
Legal notice
This product is sold strictly for in-vitro laboratory research purposes only. It is not approved for human or veterinary use, is not a drug, food, or cosmetic, and should not be misused as such. UK Peptides accepts no liability for misuse. By purchasing you confirm you are a qualified researcher aged 18 or over.