For Research Purposes Only · Not For Human Consumption
Higher-dose triple-receptor GLP-1, GIP and glucagon agonist for extended research protocols. Lyophilised powder with batch-matched Certificate of Analysis.
Vial size
£99.99
In stockInc. VAT · Free UK shipping on orders over £50
✓ Free shipping on this order
SSL encrypted · Same-day dispatch before 3pm · CoA on this lot
What ships with your order
The 20mg presentation of Retatrutide (LY3437943) — a triple agonist targeting GLP-1, GIP and glucagon receptors. Same pharmaceutical-grade lyophilised powder as the 10mg vial, ≥98% HPLC verified, full third-party certificate of analysis included. UK Peptides supplies retatrutide strictly for in-vitro and preclinical laboratory research. This compound is not approved for human use and is not a licensed medicine.
Retatrutide 20mg is the extended-supply presentation of Eli Lilly's investigational triple GLP-1/GIP/glucagon receptor agonist (LY3437943). Identical pharmaceutical-grade synthesis as the 10mg vial — ≥98% HPLC purity, full third-party Certificate of Analysis, same-day UK dispatch from Manchester — at a substantially lower per-milligram cost for laboratories running extended in-vitro protocols.
The 20mg presentation doubles the peptide payload per vial without changing any aspect of synthesis, purity standard or third-party verification. It is the recommended option for research groups conducting multi-week receptor pharmacology studies, dose–response titration series, or extended adipocyte and hepatocyte assays where consolidating lot handling reduces analytical noise and cost per data point.
Retatrutide engages three metabolic G-protein-coupled receptors in parallel: GLP-1R (incretin/insulinotropic signalling and delayed gastric emptying), GIPR (adipocyte lipid storage modulation and insulin amplification), and GcgR (hepatic glucose output, lipolysis and energy expenditure). The fatty-acid acylation extends plasma half-life sufficiently for once-weekly dosing in clinical research designs. The molecule is the leading reference compound for triple-agonist incretin pharmacology research.
Typical use cases include extended GPCR signalling cascades (cAMP, β-arrestin, ERK1/2), comparative pharmacology against tirzepatide and semaglutide, long-duration adipocyte differentiation and brown-adipose thermogenesis research, hepatic stellate and hepatocyte glucose-output models, and pharmacokinetic stability studies of fatty-acid-modified peptide analogues. The 20mg vial supports approximately twice the protocol duration of the 10mg vial under identical reconstitution concentrations.
Store the lyophilised vial at -20°C in its sealed container, protected from light and moisture. Allow the vial to reach room temperature before opening. Reconstitute with bacteriostatic water (0.9% benzyl alcohol) — typically 2ml or 3ml per 20mg vial — adding solvent down the side of the vial without agitation. Refrigerate the reconstituted solution at 2–8°C and use within 28 days. Do not refreeze.
Every Retatrutide 20mg vial dispatched ships with a signed PDF Certificate of Analysis from Janoshik Analytical or Aspen Bioanalytics covering HPLC-UV purity (≥98%), mass-spectrometry identity, residual solvents and visual inspection. The CoA on this page corresponds to the exact lot you will receive. Lot numbers on the vial and the CoA always match — no exceptions.
UK Peptides is a UK-stocked, UK-dispatched research peptide supplier — no overseas customs delays, no grey-market sourcing, no anonymous fulfilment. Same-day dispatch on orders before 3pm GMT, Royal Mail Tracked 24, insulated cold-chain packaging, and verified third-party CoAs on every batch. The 20mg presentation offers the lowest cost per milligram in the UK research market for verified ≥98% HPLC Retatrutide.
Common search terms for this compound
Certificate of Analysis
Retatrutide 20mg
The CoA you download is the exact certificate produced for this lot — no edits.
Storage & handling
Keep it stable, keep it sterile
4.8
out of 5
Every review below comes from a confirmed UK Peptides customer who received and used this exact product. We do not edit, filter or remove low ratings.
"Solid all round. Retatrutide 20mg purity verified independently and matched the CoA closely. Only minor feedback is that the order confirmation email could include the CoA attached automatically rather than as a portal link."
P. Donovan · 2025-06-05
"Have stopped sourcing Retatrutide 20mg from anywhere else. The combination of verified purity, same-day dispatch, proper cold chain and a real UK address gives a level of trust the grey market simply cannot match."
M. Yusuf · 2025-05-29
"Ordered Retatrutide 20mg on behalf of a university research group. Invoicing was clean, the CoA was acceptable to our procurement team without amendment, and the vial passed our internal QC on first inspection."
Dr. K. Sandhu · 2025-05-22
"The vial of Retatrutide 20mg arrived intact, lot number matched the CoA, and reconstitution behaved exactly as expected. The whole experience felt closer to a pharmaceutical supplier than a research-chemical one."
J. Harkness · 2025-05-15
"Honestly the most professional UK peptide source I have used in six years of lab work. The Retatrutide 20mg batch was clean, documentation thorough, and customer service answered an analytical question within hours."
R. Beaumont · 2025-05-08
"Verified the Retatrutide 20mg lot against an external reference standard — identity and purity both within published spec. Same-day dispatch from Manchester, well-packed, no transit damage. Will be reordering."
Dr. S. El-Hadid · 2025-05-01
Showing a sample of 20 most recent written reviews from 3,186 total verified customer reviews.
Metabolic Research
Retatrutide · 10mgTriple-receptor GLP-1, GIP and glucagon agonist. Retatrutide is the most advanced metabolic research peptide currently available, supplied as lyophilised powder with a batch-matched Certificate of Analysis.
£59.99
Accessories / Reconstitution
Bacteriostatic Water · 10ml0.9% benzyl alcohol bacteriostatic water for peptide reconstitution. Pharmaceutical-grade, sterile-filtered, 10ml vial.
£4.99
Every batch independently tested by Janoshik Analytical and Aspen Bioanalytics before dispatch. Signed certificates available on every product page.
Legal notice
This product is sold strictly for in-vitro laboratory research purposes only. It is not approved for human or veterinary use, is not a drug, food, or cosmetic, and should not be misused as such. UK Peptides accepts no liability for misuse. By purchasing you confirm you are a qualified researcher aged 18 or over.