For Research Purposes Only · Not For Human Consumption
Melanotan II — synthetic melanocortin receptor agonist. Extensively studied for melanogenesis and libido research.
£19.99
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What ships with your order
Melanotan II (MT-2) is a synthetic analogue of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). Lyophilised powder, ≥98% HPLC, full third-party CoA supplied.
Melanotan II (MT-2) is a synthetic cyclic heptapeptide analogue of the endogenous α-melanocyte stimulating hormone (α-MSH), studied as a non-selective melanocortin receptor agonist in melanogenesis, pigmentation, MC1R/MC4R signalling and appetite-pathway research. UK Peptides supplies MT-2 10mg lyophilised powder at ≥98% HPLC-UV verified purity with a third-party Certificate of Analysis on every batch.
Melanotan II is a synthetic cyclic analogue of α-MSH developed at the University of Arizona in the 1980s as a more stable, longer-acting research tool for studying the melanocortin receptor system. The peptide acts as a non-selective agonist at MC1R, MC3R, MC4R and MC5R receptors, making it one of the most useful reference compounds for exploring the entire melanocortin signalling network in cell-based and animal-model research.
MC1R agonism drives melanogenesis in melanocytes through cAMP-mediated upregulation of tyrosinase and downstream eumelanin synthesis — the basis of MT-2's well-documented pigmentation effects in research models. MC4R agonism is implicated in central appetite regulation and sexual function research, while MC3R and MC5R agonism are studied in inflammatory and exocrine pathway research. The cyclic structure of MT-2 confers metabolic stability significantly greater than native α-MSH, enabling longer-duration research protocols.
Published research has investigated MT-2 in melanogenesis and pigmentation studies, MC1R/MC3R/MC4R/MC5R receptor pharmacology, appetite and energy-balance research, libido and sexual function pathway studies, photoprotection and UV-response research, and inflammation modulation in MC receptor knockout models. The 10mg vial supports typical research-scale protocols with sufficient material for multi-week experiments at standard reconstitution concentrations.
Store the lyophilised vial at -20°C, sealed and protected from light. Reconstitute with bacteriostatic water (0.9% benzyl alcohol) — typically 1ml or 2ml per 10mg vial. Add solvent down the inside wall of the vial slowly; do not shake. Refrigerate the reconstituted solution at 2–8°C and use within 28 days. Do not refreeze.
Every MT-2 10mg vial is independently tested by Janoshik Analytical or Aspen Bioanalytics to ≥98% HPLC-UV purity with mass-spectrometry identity confirmation against the published molecular weight of 1,024.18 Da. The signed PDF CoA is supplied with every order and matches the vial lot number.
Melanotan II is one of the longest-established research peptides on the grey market, which means counterfeit and under-dosed product is unusually widespread. UK Peptides counters this with mandatory third-party HPLC verification on every batch, UK-stocked inventory, same-day Manchester dispatch and full lot traceability — visible directly on this product page.
Common search terms for this compound
Certificate of Analysis
MT-2 10mg
The CoA you download is the exact certificate produced for this lot — no edits.
Storage & handling
Keep it stable, keep it sterile
4.8
out of 5
Every review below comes from a confirmed UK Peptides customer who received and used this exact product. We do not edit, filter or remove low ratings.
"Ordered Melanotan II 10mg on behalf of a university research group. Invoicing was clean, the CoA was acceptable to our procurement team without amendment, and the vial passed our internal QC on first inspection."
Dr. K. Sandhu · 2025-05-22
"The vial of Melanotan II 10mg arrived intact, lot number matched the CoA, and reconstitution behaved exactly as expected. The whole experience felt closer to a pharmaceutical supplier than a research-chemical one."
J. Harkness · 2025-05-15
"Honestly the most professional UK peptide source I have used in six years of lab work. The Melanotan II 10mg batch was clean, documentation thorough, and customer service answered an analytical question within hours."
R. Beaumont · 2025-05-08
"Verified the Melanotan II 10mg lot against an external reference standard — identity and purity both within published spec. Same-day dispatch from Manchester, well-packed, no transit damage. Will be reordering."
Dr. S. El-Hadid · 2025-05-01
"Ordering Melanotan II 10mg from UK Peptides is now a routine line item in our monthly research budget. Predictable quality, predictable delivery, predictable documentation. That is exactly what a working lab needs."
T. Vasquez · 2025-04-24
"Good purity on the Melanotan II 10mg lot, fast dispatch, well-packed. Only suggestion would be a slightly larger ice pack for warmer weather deliveries — vial itself was fine either way."
I. Marsh · 2025-04-17
Showing a sample of 20 most recent written reviews from 4,655 total verified customer reviews.
Accessories / Reconstitution
Bacteriostatic Water · 10ml0.9% benzyl alcohol bacteriostatic water for peptide reconstitution. Pharmaceutical-grade, sterile-filtered, 10ml vial.
£4.99
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Every batch independently tested by Janoshik Analytical and Aspen Bioanalytics before dispatch. Signed certificates available on every product page.
Legal notice
This product is sold strictly for in-vitro laboratory research purposes only. It is not approved for human or veterinary use, is not a drug, food, or cosmetic, and should not be misused as such. UK Peptides accepts no liability for misuse. By purchasing you confirm you are a qualified researcher aged 18 or over.