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Antioxidant≥98% HPLC
Batch —
Glutathione 1500mg vial
Third-party tested
CoA available
UK dispatched
4.8· 2,965 verified reviewsAntioxidant / Skin Research

Buy Glutathione 1500mg UK | Research Grade

Reduced L-Glutathione (GSH). Master intracellular antioxidant researched for oxidative stress, detoxification and skin brightening pathways.

£34.99

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UK Peptides Quality Standards

Every batch is independently HPLC-tested by a third-party laboratory. Lot-matched Certificates of Analysis are available on request. For any quality-related query, contact support with your batch number and order ID.

What ships with your order

  • 1 × Glutathione 1500mg — lyophilised, sealed glass vial.
  • Signed CoA for batch this lot — HPLC-UV purity + mass-spec identity, by Janoshik Analytical.
  • Royal Mail Tracked 24 — same-day dispatch on orders before 6pm GMT, Mon–Fri.
Research Compound

About Glutathione

Glutathione (γ-L-glutamyl-L-cysteinylglycine) is a tripeptide antioxidant present in nearly every cell, and the most abundant intracellular thiol in mammalian biology. It is central to redox homeostasis, phase-II detoxification, and melanogenesis regulation via tyrosinase inhibition. UK Peptides supplies reduced L-Glutathione (GSH) 1500mg as ≥98% HPLC lyophilised powder.

Research areas

  • Oxidative stress models
  • Phase-II detoxification
  • Tyrosinase / melanogenesis
  • Redox homeostasis
  • Hepatocyte research
In-depth guide

Glutathione 1500mg — research overview, mechanism & protocol guidance

Glutathione (γ-L-glutamyl-L-cysteinylglycine) is a tripeptide antioxidant present in almost every cell — the most abundant intracellular thiol in mammalian biology. It is central to redox homeostasis, phase-II detoxification and melanogenesis regulation via tyrosinase inhibition. UK Peptides supplies reduced L-Glutathione (GSH) 1500mg as ≥98% HPLC lyophilised powder with a signed third-party Certificate of Analysis.

What is Glutathione? The master intracellular antioxidant

Glutathione is a small tripeptide of glutamate, cysteine and glycine, distinguished by an unusual γ-carboxyl peptide bond between glutamate and cysteine that confers resistance to peptidase degradation. Cellular concentrations are exceptionally high — typically 1–10mM inside cells — making it the dominant redox buffer of intracellular biology. It exists in equilibrium between the reduced (GSH) and oxidised disulphide (GSSG) forms; the GSH:GSSG ratio is a widely-used biomarker of oxidative stress in research.

Glutathione mechanism and research pathways

Glutathione's cysteine thiol group is the reactive centre for redox reactions, scavenging reactive oxygen species directly, serving as substrate for glutathione peroxidases in peroxide detoxification, and forming conjugates with electrophilic xenobiotics via glutathione S-transferases in phase-II detoxification. Additionally, glutathione inhibits tyrosinase in melanocyte research models, which underlies its use as a reference compound in melanogenesis and skin brightening research.

Glutathione research applications

Published research has investigated glutathione in oxidative-stress and redox-biology models, hepatic phase-II detoxification research, tyrosinase and melanogenesis regulation, mitochondrial-function studies, glutathione peroxidase and glutathione reductase enzyme research, and comparative antioxidant pharmacology against N-acetyl cysteine and other thiol antioxidants.

Storage, reconstitution and handling

Store the lyophilised glutathione powder at -20°C, sealed and protected from light. Reduced glutathione oxidises rapidly on exposure to air — keep vials tightly sealed and reconstitute immediately before use where possible. Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Refrigerate the reconstituted solution at 2–8°C and use within 14 days. For longer storage, aliquot and freeze at -20°C.

≥98% HPLC purity, third-party verified

Every Glutathione 1500mg lot is independently HPLC-UV tested to ≥98% purity by Janoshik Analytical or Aspen Bioanalytics, with mass-spectrometry identity confirmation against the published molecular weight of 307.32 Da (reduced form). The signed PDF Certificate of Analysis is supplied with every order.

Why UK Peptides for Glutathione

Glutathione is particularly sensitive to poor storage — a vial oxidised in transit is analytically inferior before it reaches your bench. UK Peptides ships with insulated mailers and ice packs, dispatches same-day from Manchester and provides third-party HPLC verification on every batch confirming reduced-form purity at the point of dispatch.

Common search terms for this compound

  • buy Glutathione UK
  • GSH 1500mg research
  • reduced glutathione UK
  • antioxidant research peptide
  • glutathione HPLC verified
  • tyrosinase research compound
  • glutathione CoA
References & further reading

Primary sources cited on this page

Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a small tripeptide antioxidant found at millimolar intracellular concentrations in almost every mammalian cell. It is central to redox homeostasis, phase-II detoxification via glutathione S-transferases, and glutathione peroxidase-mediated peroxide detoxification.

Peer-reviewed literature & regulatory records

  1. [1] Meister & Anderson, 'Glutathione'
    Annual Review of Biochemistry, 1983;52:711-760
  2. [2] Wu et al., 'Glutathione metabolism and its implications for health'
    The Journal of Nutrition, 2004;134(3):489-492
  3. [3] Forman, Zhang & Rinna, 'Glutathione: overview of its protective roles, measurement, and biosynthesis'
    Molecular Aspects of Medicine, 2009;30(1-2):1-12
  4. [4] Villarama & Maibach, 'Glutathione as a depigmenting agent: an overview'
    International Journal of Cosmetic Science, 2005;27(3):147-153
  5. [5] PubChem CID 745 — Glutathione (reduced)
    NCBI PubChem

Regulatory & compliance notice

This product is supplied strictly for in-vitro laboratory research. It is not a licensed medicine in the United Kingdom, is not approved by the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency for human or veterinary use, and is not intended to diagnose, treat, cure or prevent any disease. Nothing on this page constitutes medical advice.

External links point to primary literature or regulatory records and open in a new tab. Citations are provided so the reader can independently verify every factual claim made on this page. Last reviewed 22 July 2026.

Certificate of Analysis

Glutathione 1500mg

Independent lab
Janoshik Analytical
Batch number
—
Method
HPLC-UV + MS
Result
≥98% HPLC
Download CoA (PDF) — Glutathione 1500mg

The CoA you download is the exact certificate produced for this lot — no edits.

Storage & handling

Keep it stable, keep it sterile

Storage: Store lyophilised powder at -20°C in a sealed vial. Protect from light and moisture. Allow the vial to reach room temperature before opening to prevent condensation entering the vial. Do not store in a frost-free freezer. Reconstitution: Reconstitute using bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial — do not shake. Allow to dissolve gently at room temperature. Reconstituted stability: After reconstitution, store at 2–8°C and use within 14 days. Glutathione oxidises on prolonged exposure to air — keep vials sealed between draws. Shipping: All vials are dispatched in insulated mailers with ice packs to maintain cold chain during Royal Mail Tracked 24 transit.
+ Add Bacteriostatic Water (£4.99) →
Customer reviews

Trusted by 2,965 verified researchers

4.8

out of 5

Every review below comes from a confirmed UK Peptides customer who received and used this exact product. We do not edit, filter or remove low ratings.

  • 5 star
    92%
  • 4 star
    6%
  • 3 star
    1%
  • 2 star
    0.5%
  • 1 star
    0.5%
  • Verified

    "Verified the Glutathione 1500mg lot against an external reference standard — identity and purity both within published spec. Same-day dispatch from Manchester, well-packed, no transit damage. Will be reordering."

    Dr. S. El-Hadid · 2025-05-01

  • Verified

    "Ordering Glutathione 1500mg from UK Peptides is now a routine line item in our monthly research budget. Predictable quality, predictable delivery, predictable documentation. That is exactly what a working lab needs."

    T. Vasquez · 2025-04-24

  • Verified

    "Good purity on the Glutathione 1500mg lot, fast dispatch, well-packed. Only suggestion would be a slightly larger ice pack for warmer weather deliveries — vial itself was fine either way."

    I. Marsh · 2025-04-17

  • Verified

    "Ordered Glutathione 1500mg at 1pm on a Tuesday and it landed on my bench Wednesday morning. The insulated mailer was still cold, the vial was sealed properly, and the CoA was in my inbox before the courier knocked. Exactly the kind of supplier serious research labs need."

    James T. · 2025-11-18

  • Verified

    "Third order of Glutathione 1500mg from UK Peptides and the consistency is remarkable. HPLC trace matches the certificate to two decimal places, batch numbers match the vial sticker, no surprises. This is how it should be done."

    Rachel K. · 2025-11-10

  • Verified

    "Independent verification on a sample of the Glutathione 1500mg lot confirmed the stated purity within margin of error. Documentation, packaging and cold chain were all faultless. Switched my entire group over from a US supplier last quarter."

    Dr. P. Hargreaves · 2025-11-03

Showing a sample of 20 most recent written reviews from 2,965 total verified customer reviews.

FAQ

Glutathione 1500mg — common questions

Research Library

Further reading on Glutathione

Peer-referenced articles from our research library covering mechanism, evidence and handling.

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Every batch independently tested by Janoshik Analytical and Aspen Bioanalytics before dispatch. Signed certificates available on every product page.

Legal notice

This product is sold strictly for in-vitro laboratory research purposes only. It is not approved for human or veterinary use, is not a drug, food, or cosmetic, and should not be misused as such. UK Peptides accepts no liability for misuse. By purchasing you confirm you are a qualified researcher aged 18 or over.