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Selank 10mg vial

Nootropic / Anxiolytic Research

Selank 10mg

Selank peptide — the tuftsin-derived heptapeptide TKPRPGP, lyophilised. Preclinical work on GABA-A, enkephalinase and BDNF expression.

Vial size

Quantity

£24.99

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Handling

Storage

Sealed vial
-20°C, protect from light
Once reconstituted
Once reconstituted, store at 2–8°C (refrigerated). Use within 28 days.
Diluent
Bacteriostatic water (0.9% benzyl alcohol)
Shipping
Royal Mail Tracked 24
Add bacteriostatic water · £1.99
FAQ

Selank — common questions

7 more questions
Research Compound

About Selank

Selank is a synthetic heptapeptide analogue of the immunomodulatory tetrapeptide tuftsin, extended with a C-terminal Pro-Gly-Pro motif for protease resistance and developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It appears in the literature as Selank, as the sequence shorthand TKPRPGP, and under the development code TP-7. The published record is preclinical and predominantly conducted in rats: reported inhibition of enkephalin-degrading enzymes measured on plasma enkephalinase activity, reported effects on GABA-A receptor expression in the hippocampus rather than direct binding at the receptor, and regulation of BDNF expression following intranasal administration.

More about this listing

Tuftsin signals through the receptor neuropilin-1; Selank has no identified receptor of its own, and whether the extension preserves that engagement is not established. PubMed indexes roughly 135 Selank records, against about 690 for tuftsin itself. No Western regulator has assessed the compound. Selank has a registration history in the Russian Federation and holds no MHRA, EMA or FDA authorisation. UK Peptides supplies it as 99.99% HPLC lyophilised powder with a signed third-party Certificate of Analysis, strictly for in-vitro and preclinical laboratory research. It is not a licensed medicine and is not for human or veterinary use.

Research areas

  • GABA-A receptor expression
  • Enkephalinase inhibition
  • BDNF expression (rodent)
  • Anxiolytic-pathway research (preclinical)
  • Tuftsin lineage & immunomodulation
Five UK Peptides vials in an open presentation box

The range

One vial, or the set.

Every vial in the range is lyophilised, labelled and lot-numbered the same way, with the certificate for its lot linked from its own product page. Pictured: BPC-157, TB-500, GHK-Cu, Glow and Retatrutide.

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Compound Profile

Technical profile

Read the full Selank technical profile7 sections

Selank — also written as the Selank peptide, and appearing in older Russian-language records under the development code TP-7 — is a synthetic heptapeptide analogue of tuftsin, developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Its sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro: the tuftsin tetrapeptide with a Pro-Gly-Pro extension that confers protease resistance.

The published record is preclinical and predominantly rodent, covering inhibition of enkephalin-degrading enzymes, GABA-A receptor expression and BDNF expression. UK Peptides supplies Selank 10mg as 99.99% HPLC lyophilised powder with a signed third-party Certificate of Analysis, for laboratory research only.

01

Selank identity: TKPRPGP, CAS 129954-34-3 and the TP-7 development code

Selank appears in the record under several labels. TP-7 is the development code, used in older Russian-language papers that never print the name; TKPRPGP is the sequence shorthand. Names are ambiguous and identifiers are not, so a certificate of analysis should be checked against CAS Registry Number 129954-34-3, PubChem CID 11765600 and UNII TS9JR8EP1G, with molecular formula C33H57N11O9 and a molecular weight of 751.88 Da.

Two practical consequences follow from the sequence itself. Selank contains no methionine, so mass-spectrometry identity confirmation should show no +16 Da oxidation satellite — if one is present, something other than simple methionine oxidation needs explaining. And there is no tryptophan, tyrosine or phenylalanine in the sequence, so Selank has almost no usable absorbance near 280 nm; concentration has to be established gravimetrically against a certified peptide content or by another analytical route, rather than by the standard spectrophotometric method.

Synthetic peptides of this kind are also isolated as acetate or trifluoroacetate salts, so the counter-ion contributes to the gross weight of powder in the vial and net peptide content should be stated separately on the certificate.

02

Selank peptide research applications

The 10mg vial supports extended research protocols at standard bench working concentrations. The published literature — roughly 135 indexed PubMed records, against about 690 for its parent peptide tuftsin — is preclinical and predominantly conducted in rats. Reported areas of investigation include:

  • Enkephalin-degrading enzyme (enkephalinase) inhibition
  • GABA-A receptor expression in rodent hippocampus
  • BDNF expression following intranasal administration in rats
  • Anxiolytic-like behaviour in animal models
  • Ethanol-induced memory impairment models in rats
  • Morphine-withdrawal models in rats
  • Tuftsin lineage and immunomodulatory pathway studies
03

Semax and Selank: one design method, two unrelated parents

Both compounds came out of the Institute of Molecular Genetics of the Russian Academy of Sciences, and both were built the same way — take a short bioactive fragment of a larger endogenous peptide and append Pro-Gly-Pro to make it durable. The fragments have nothing to do with one another.

Semax retains a fragment of ACTH, a pituitary hormone, and its literature centres on neurotrophin expression and neuroprotection in ischaemia models. Selank retains tuftsin, an immunoglobulin-derived tetrapeptide. Two peptides sharing a stabilising tail are no more related than two proteins sharing a purification tag: the extension is a durability device, not the source of activity.

Semax is 813.94 Da against Selank's 751.88 Da, and PubMed indexes roughly 231 Semax records to Selank's 135. Both also carry a BDNF literature from the same period and from partly overlapping author groups, which is better read as a pattern within one research programme than as independent confirmation of either. Neither holds a Western marketing authorisation.

04

Regulatory position and supply basis

Selank has a registration history in the Russian Federation and holds no authorisation from the MHRA, the EMA or the FDA. A national marketing authorisation is one regulator's assessment of one submission against its own standards; it does not transfer between jurisdictions, and it is not evidence that can be repeated elsewhere as an effect.

Nothing on this page states or implies that Selank treats, improves or affects any condition in any person, because no such claim is supported by the published record.

05

Storage and stability

Store the lyophilised vial at -20°C, sealed and protected from light. Refrigerate the reconstituted solution at 2–8°C and use within 28 days. Do not refreeze.

06

99.99% HPLC purity — independently verified

Every Selank 10mg lot is independently HPLC-UV tested to 99.99% purity by an accredited independent laboratory, with mass-spectrometry identity confirmation against the published molecular weight of 751.88 Da and the formula C33H57N11O9. Seven residues is a short synthesis with few opportunities for truncation, so purity figures for this compound are typically high and an unexpectedly low one deserves scrutiny.

The signed Certificate of Analysis can be viewed on this page and matches the lot number printed on the vial. A purity figure with no chromatogram behind it is an assertion rather than a measurement, which is why the chromatogram is published rather than the number alone.

07

Buying Selank peptide in the UK

Selank sits alongside Semax as one of the most frequently counterfeited research peptides on the grey market, and there is no UK licensed reference product against which a vial can be checked. UK Peptides answers that with mandatory third-party verification on every lot, UK-held stock, same-day Manchester dispatch, and lot traceability from the vial sticker to the signed Certificate of Analysis on this page.

Selank peptide is supplied here in one form only: a 10mg lyophilised powder in a sealed vial, for laboratory research.

References & further reading

Primary sources cited on this page

Sources & related pages4 sources · 17 related

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro, shorthand TKPRPGP) analogue of the endogenous immunomodulatory tetrapeptide tuftsin, extended with a C-terminal Pro-Gly-Pro sequence for metabolic stability. It carries CAS Registry Number 129954-34-3, PubChem CID 11765600 and UNII TS9JR8EP1G, with molecular formula C33H57N11O9 and molecular weight 751.88 Da, and appears in older Russian-language literature under the development code TP-7.

Regulatory & compliance notice

This product is supplied strictly for in-vitro laboratory research. It is not a licensed medicine in the United Kingdom, is not approved by the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency for human or veterinary use, and is not intended to diagnose, treat, cure or prevent any disease. Nothing on this page constitutes medical advice.

Last reviewed 22 July 2026.

Every batch independently tested by an accredited independent laboratory before dispatch. The signed certificate for this lot is published on this page.

Third-party HPLC-UV testing Lot-matched CoA on every order Batch-traceable from dispatch

Legal notice

This product is sold strictly for in-vitro laboratory research purposes only. It is not approved for human or veterinary use, is not a drug, food, or cosmetic, and should not be misused as such. UK Peptides accepts no liability for misuse. By purchasing you confirm you are a qualified researcher aged 18 or over.

Selank 10mg

£24.99