What is BPC-157's CAS number?

137525-51-0, corresponding to PubChem CID 9941957 at 1419.5 Da. The identifiers agree with each other, which is not true of every research peptide.

The development code under which BPC-157 entered clinical trials for inflammatory bowel disease. The clinical literature is indexed under it.

Why does proline content matter for purity?

Proline coupling is sterically hindered and is a recognised difficult step in solid-phase synthesis. Four prolines in fifteen residues deserve attention when reading a purity figure.

BPC-157 CAS Number and Chemical Identity

The short answer

BPC-157 carries CAS Registry Number 137525-51-0, PubChem CID 9941957 and UNII 8ED8NXK95P, with molecular formula C62H98N16O22 and molecular weight 1419.5 Da. Unlike TB-500 or GHK-Cu, one name maps cleanly to one compound.

Key facts

CAS Registry Number: 137525-51-0
PubChem CID: 9941957
UNII: 8ED8NXK95P
Molecular formula: C62H98N16O22
Molecular weight: 1419.5 Da
Development codes: PL-14736, PLD-116, PL-10
Also indexed as: Bepecin

A category without an identity problem

This matters because the neighbouring categories have one. TB-500 shares a name with a protein 5.6 times its mass; GHK-Cu is routinely quoted with the free peptide's molecular weight. BPC-157 has one CAS number, one PubChem record, one molecular weight and one sequence, and they agree with each other. The identifier is unambiguous.

The development codes

PL-14736 is the code under which BPC-157 entered clinical development for inflammatory bowel disease, and it is the term the clinical literature uses. PLD-116 and PL-10 also appear, along with the name Bepecin. Searching the codes surfaces records the compound name misses; the clinical work in particular is indexed under PL-14736.

Research material referenced

BPC-157 5mg, third-party HPLC tested

Buy BPC-157 · £15.99

Confirming identity

Mass spectrometry against 1419.5 Da for C62H98N16O22. The sequence contains no cysteine and no methionine, so neither disulfide species nor the +16 Da oxidation satellite should appear; their presence indicates something other than the stated compound.

Confirming purity

Reverse-phase HPLC against truncated and deletion sequences. Fifteen residues is a moderate synthesis, longer than the heptapeptides in neighbouring categories and with correspondingly more opportunity for incomplete coupling. The four prolines are relevant here too: proline coupling is sterically hindered and is a recognised difficult step in solid-phase synthesis, so a peptide with four of them warrants attention to the purity figure.

The acetate question

Synthetic peptides are typically supplied as salts, and the counter-ion contributes to gross vial weight. Net peptide content is lower than the powder weighs, and a certificate should state the two separately. This is general rather than specific to BPC-157, but it applies here as everywhere.

Frequently asked questions

What is BPC-157's CAS number?: 137525-51-0, corresponding to PubChem CID 9941957 at 1419.5 Da. The identifiers agree with each other, which is not true of every research peptide.
What is PL-14736?: The development code under which BPC-157 entered clinical trials for inflammatory bowel disease. The clinical literature is indexed under it.
Why does proline content matter for purity?: Proline coupling is sterically hindered and is a recognised difficult step in solid-phase synthesis. Four prolines in fifteen residues deserve attention when reading a purity figure.

Extended research context

The BPC-157 (Pentadecapeptide) deep dive

Deep dive: the pentadecapeptide sequence

BPC-157 is a synthetic pentadecapeptide with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. It is derived from a fragment identified in human gastric juice by the Zagreb research group (Sikirić and colleagues), whose body of published work spans three decades and covers models ranging from tendon repair to gut integrity. The 'BPC' initials stand for 'body protection compound', the group's original characterisation term.

Two forms: acetate salt vs arginate

BPC-157 is supplied most commonly as an acetate salt; a small subset of suppliers offer the arginate form, which has slightly different solubility and stability properties. For research reproducibility, keep the salt form consistent across a study and confirm which form the CoA specifies (mass ± counterion changes the reading).

Reading a BPC-157 CoA

A trustworthy BPC-157 CoA lists HPLC purity (target ≥98% area), mass-spec confirmation (~1,419 Da for the free peptide), water content (Karl Fischer), acetate content, and residual solvents. Some batches also include endotoxin data. Any missing category is a red flag for a compromised supply chain.

Research applications

▸Cell-culture models of gut epithelial integrity
▸Tendon fibroblast migration and collagen-synthesis assays
▸Angiogenesis models involving VEGF and NO signalling
▸Stability studies comparing acetate vs arginate salt forms
▸Analytical reference for pentadecapeptide HPLC methods

Handling checklist

✓Store lyophilised vial at −20 °C long-term (2–8 °C short-term)
✓Reconstitute with bacteriostatic water; a 5 mg vial dissolves cleanly
✓Aliquot reconstituted solution; keep refrigerated 2–8 °C, use within 28 days
✓Protect from light and repeated warming
✓Verify CoA: HPLC ≥98%, mass ~1,419 Da, salt form declared

Common research-handling mistakes

Learnt from thousands of researcher orders across our UK labs.

✗ Mixing acetate and arginate BPC-157 across a study

Fix: Choose one salt form and stay with it. Different masses and solubility.

✗ Assuming stability at room temperature

Fix: Refrigerate reconstituted solution; discard after 28 days.

✗ Buying without a CoA

Fix: Only source from suppliers that publish batch HPLC + mass-spec data.

Continue researching

Peer-reviewed guides, comparators and matched reference materials.

Primary sources & clinical trials

Peer-reviewed research and registered trials from PubMed, ClinicalTrials.gov, PubChem, FDA and NIH. All links open in a new tab and point to the primary source, so every claim can be verified at origin.

UKP

Written and reviewed by

The UK Peptides Editorial Team · Research library, UK Peptides

The editorial team is responsible for supplier selection, batch release decisions and the content published in this research library. Every article here is sourced to primary literature and every product page to a signed third-party certificate. Corrections are made in place and the review date updated.

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